Autonomic Pharmacology

In this exercise you are expected to use your understanding of the autonomic nervous system and the actions of some standard pharmacological agents acting on the autonomic nervous system to localise the site of ocular dysfunction in four patients. When you have completed the exercise you should be able to determine whether the cause of the deficit is sympathetic or parasympathetic, prejunctional or postjunctional.

The simulation has only two sections, one where you can alter the ambient light level, and one where you can administer pharmacological agents to the patient's eyes. The reactivity of the eye to light should be used to form a hypothesis regarding the likely autonomic dysfunction of each patient. The hypothesis can then be tested using the pharmacological agents. The sequence of the exercises is important to the optimal learning outcomes and you should not move on to investigate the action of the drugs until you have formed your hypothesis for the patient.